Firefighters from Central Scotland Fire and Rescue Service are currently tackling a blaze at a waste treatment facility at Kilbagie Mill, a mile north of Kincardine.
The call was received at 8.06am today (Thursday) and 17 appliances were initially sent to the scene. The site is operated by Oran Environmental Solutions. No-one has been injured and all staff are safe.
The fire is in a large warehouse which contains recyclable material such as clothing, mattresses and waste paper.
Fire crews are currently providing protective spray jets to protect surrounding properties and there are nine fire appliances on currently on scene supported by Duty Officers. The incident is under control.
Chief Fire Officer with Central Scotland Fire and Rescue Service Kenneth Taylor said: "Given the scale of combustible material involved it's likely this incident will be protracted with crews having to remain on scene over the next day or two for damping down. We do hope however to be able to make inroads over the next few hours in order that we can reduce the extent of the smoke plume.
"We are working with all our partners including, the police, SEPA, representatives from Oran, Scottish Power and Clackmannanshire Council to assist in bringing about a resolution."
Central Scotland Police is advising motorists to reduce their speed, as smoke is blowing across both north and southbound carriageways near the A876 Kilbagie and Higgins Neuk roundabouts.